Then, what is Kyrle disease?
Kyrle disease is a perforating skin condition characterized by the presence of large keratotic papules distributed widely throughout the body. The papules contain a central keratotic plug, which histologically correlates with keratin and necrotic debris.
Likewise, what is keratosis Follicularis et Parafollicularis in Cutem Penetrans? Kyrle disease was first described in 1916 by Kyrle as 'hyperkeratosis follicularis et follicularis in cutem penetrans' and identified as a perforating disease. Kyrle disease is characterised by the formation of large papules with central keratin plugs and is often associated with hepatic, renal or diabetic disorders.
One may also ask, what is perforating folliculitis?
Perforating disorders are characterized by transepidermal elimination of altered keratin or dermal connective tissue material. Perforating folliculitis may present as an isolated finding, apparently unrelated to other disease states, but also can be associated with chronic renal failure and diabetes mellitus.
What is Flegel disease?
Flegel disease is a rare dermatosis characterized by asymptomatic hyperkeratotic papules predominantly on the dorsa of the feet and lower legs. Clinical input is often very helpful in making a diagnosis histopathologically.